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In April 2025 the company announced it was struggling with more than US $1.4 billion debt and were filing for bankruptcy (Ferguson)

Heart Failure HF and its specific subtype HFpEF represent two significant therapeutic areas where GLP-1 agonists are being developed

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Consult a licensed healthcare provider before starting, stopping, or changing any medication

However, the results showed that in addition to the cardiovascular safety of GLP-1 receptor agonists, some drugs in the class can have influence on major adverse cardiovascular event (MACE) reduction compared to placebo (37)